© 1996 British Society for Rheumatology
research-article |
REMISSION IN A PROSPECTIVE STUDY OF PATIENTS WITH RHEUMATOID ARTHRITIS. AMERICAN RHEUMATISM ASSOCIATION PRELIMINARY REMISSION CRITERIA IN RELATION TO THE DISEASE ACTIVITY SCORE
*Departments of Rheumatology The Netherlands
Departments of Statistics, University Hospital Nijmegen The Netherlands
Department of Rheumatology, University Hospital Groningen The Netherlands
Correspondence to:
Correspondence to: P. L. C. M. van Riel, Department of Rheumatology, University Hospital Nijmegen, Geert Grooteplein 8, 6525 GA Nijmegen, The Netherlands.
In a prospective follow-up study of patients with early-onset rheumatoid arthritis, the prevalence of remission according to the 1981 American Rheumatism Association (ARA) preliminary criteria was evaluated. A total of 227 patients with a median follow-up of 3.9 yr and a total of 2832 follow-up visits were studied. The ARA remission criteria were fulfilled in 9.5% of these visits. The percentage of patients with at least one visit fulfilling the ARA criteria was for years 2–6 
25%. Each year, 15% of the patients were in remission for at least two consecutive visits. A comparison was made between the ARA remission criteria and the Disease Activity Score (DAS). DAS < 1.6 corresponded with being in remission according to the ARA criteria. The DAS is being proposed as a tool to define remission because absence of disease activity should be measured using the same method as for higher levels of disease activity, preferably on a continuous scale.
KEY WORDS: Rheumatoid arthritis, Disease Activity Score, Remission
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  C. A. Scire, C. Montecucco, V. Codullo, O. Epis, M. Todoerti, and R. Caporali Ultrasonographic evaluation of joint involvement in early rheumatoid arthritis in clinical remission: power Doppler signal predicts short-term relapse Rheumatology, September 1, 2009; 48(9): 1092 - 1097. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K Pavelka, K Jarosova, D Suchy, L Senolt, K Chroust, L Dusek, and J Vencovsky Increasing the infliximab dose in rheumatoid arthritis patients: a randomised, double blind study failed to confirm its efficacy Ann Rheum Dis, August 1, 2009; 68(8): 1285 - 1289. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. MERTENS and J. A. SINGH Anakinra for Rheumatoid Arthritis: A Systematic Review J Rheumatol, June 1, 2009; 36(6): 1118 - 1125. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G Wells, J-C Becker, J Teng, M Dougados, M Schiff, J Smolen, D Aletaha, and P L C M van Riel Validation of the 28-joint Disease Activity Score (DAS28) and European League Against Rheumatism response criteria based on C-reactive protein against disease progression in patients with rheumatoid arthritis, and comparison with the DAS28 based on erythrocyte sedimentation rate Ann Rheum Dis, June 1, 2009; 68(6): 954 - 960. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S M van der Kooij, Y P M Goekoop-Ruiterman, J K de Vries-Bouwstra, M Guler-Yuksel, A H Zwinderman, P J S M Kerstens, P A H M van der Lubbe, W M de Beus, B A M Grillet, H K Ronday, et al. Drug-free remission, functioning and radiographic damage after 4 years of response-driven treatment in patients with recent-onset rheumatoid arthritis Ann Rheum Dis, June 1, 2009; 68(6): 914 - 921. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. RINTELEN, P. M. HAINDL, J. SAUTNER, B. A. LEEB, C. DEUTSCH, and B. F. LEEB The Rheumatoid Arthritis Disease Activity Index-5 in Daily Use. Proposal for Disease Activity Categories J Rheumatol, May 1, 2009; 36(5): 918 - 924. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. WOLFE, M. BOERS, D. FELSON, K. MICHAUD, and G. A. WELLS Remission in Rheumatoid Arthritis: Physician and Patient Perspectives J Rheumatol, May 1, 2009; 36(5): 930 - 933. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I Hafstrom, K Albertsson, A Boonen, D van der Heijde, R Landewe, B Svensson, and for the BARFOT Study Group Remission achieved after 2 years treatment with low-dose prednisolone in addition to disease-modifying anti-rheumatic drugs in early rheumatoid arthritis is associated with reduced joint destruction still present after 4 years: an open 2-year continuation study Ann Rheum Dis, April 1, 2009; 68(4): 508 - 513. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D Aletaha, R Landewe, T Karonitsch, J Bathon, M Boers, C Bombardier, S Bombardieri, H Choi, B Combe, M Dougados, et al. Reporting disease activity in clinical trials of patients with rheumatoid arthritis: EULAR/ACR collaborative recommendations Ann Rheum Dis, October 1, 2008; 67(10): 1360 - 1364. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T Karonitsch, D Aletaha, M Boers, S Bombardieri, B Combe, M Dougados, P Emery, D Felson, J Gomez-Reino, E Keystone, et al. Methods of deriving EULAR/ACR recommendations on reporting disease activity in clinical trials of patients with rheumatoid arthritis Ann Rheum Dis, October 1, 2008; 67(10): 1365 - 1373. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E Tanaka, A Mannalithara, E Inoue, M Hara, T Tomatsu, N Kamatani, G Singh, and H Yamanaka Efficient management of rheumatoid arthritis significantly reduces long-term functional disability Ann Rheum Dis, August 1, 2008; 67(8): 1153 - 1158. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Westhoff, R. Rau, and A. Zink Rheumatoid arthritis patients who smoke have a higher need for DMARDs and feel worse, but they do not have more joint damage than non-smokers of the same serological group Rheumatology, June 1, 2008; 47(6): 849 - 854. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. Cantini, L. Niccoli, C. Nannini, E. Cassara, P. Pasquetti, I. Olivieri, and C. Salvarani Frequency and duration of clinical remission in patients with peripheral psoriatic arthritis requiring second-line drugs Rheumatology, June 1, 2008; 47(6): 872 - 876. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Matsui, Y. Kuga, A. Kaneko, J. Nishino, Y. Eto, N. Chiba, M. Yasuda, K. Saisho, K. Shimada, and S. Tohma Disease Activity Score 28 (DAS28) using C-reactive protein underestimates disease activity and overestimates EULAR response criteria compared with DAS28 using erythrocyte sedimentation rate in a large observational cohort of rheumatoid arthritis patients in Japan Ann Rheum Dis, September 1, 2007; 66(9): 1221 - 1226. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Sokka, H. Makinen, P. Hannonen, and T. Pincus Most people over age 50 in the general population do not meet ACR remission criteria or OMERACT minimal disease activity criteria for rheumatoid arthritis Rheumatology, June 1, 2007; 46(6): 1020 - 1023. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. L. Scott Early rheumatoid arthritis Br. Med. Bull., May 31, 2007; (2007) ldm011v1. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y. P.M. Goekoop-Ruiterman, J. K. de Vries-Bouwstra, C. F. Allaart, D. van Zeben, P. J.S.M. Kerstens, J. M. W. Hazes, A. H. Zwinderman, A. J. Peeters, J. M. de Jonge-Bok, C. Mallee, et al. Comparison of Treatment Strategies in Early Rheumatoid Arthritis: A Randomized Trial Ann Intern Med, March 20, 2007; 146(6): 406 - 415. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G Cohen, L Gossec, M Dougados, A Cantagrel, P Goupille, J. Daures, N Rincheval, and B Combe Radiological damage in patients with rheumatoid arthritis on sustained remission Ann Rheum Dis, March 1, 2007; 66(3): 358 - 363. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K Forslind, I Hafstrom, M Ahlmen, B Svensson, and for the BARFOT Study Group Sex: a major predictor of remission in early rheumatoid arthritis? Ann Rheum Dis, January 1, 2007; 66(1): 46 - 52. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J Fransen, C Antoni, P J Mease, W Uter, A Kavanaugh, J R Kalden, and P L C M Van Riel Performance of response criteria for assessing peripheral arthritis in patients with psoriatic arthritis: analysis of data from randomised controlled trials of two tumour necrosis factor inhibitors Ann Rheum Dis, October 1, 2006; 65(10): 1373 - 1378. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M E Weinblatt, E C Keystone, D E Furst, A F Kavanaugh, E K Chartash, and O G Segurado Long term efficacy and safety of adalimumab plus methotrexate in patients with rheumatoid arthritis: ARMADA 4 year extended study Ann Rheum Dis, June 1, 2006; 65(6): 753 - 759. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R Landewe, D van der Heijde, S van der Linden, and M Boers Twenty-eight-joint counts invalidate the DAS28 remission definition owing to the omission of the lower extremity joints: a comparison with the original DAS remission Ann Rheum Dis, May 1, 2006; 65(5): 637 - 641. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D van der Heijde, L Klareskog, M Boers, R Landewe, C Codreanu, H D Bolosiu, R Pedersen, S Fatenejad, and for TEMPO Investigators Comparison of different definitions to classify remission and sustained remission: 1 year TEMPO results Ann Rheum Dis, November 1, 2005; 64(11): 1582 - 1587. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M Ostergaard, A Duer, H Nielsen, J S Johansen, E Narvestad, B J Ejbjerg, B Baslund, J M Moller, H S Thomsen, and J Petersen Magnetic resonance imaging for accelerated assessment of drug effect and prediction of subsequent radiographic progression in rheumatoid arthritis: a study of patients receiving combined anakinra and methotrexate treatment Ann Rheum Dis, October 1, 2005; 64(10): 1503 - 1506. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H Makinen, H Kautiainen, P Hannonen, and T Sokka Is DAS28 an appropriate tool to assess remission in rheumatoid arthritis? Ann Rheum Dis, October 1, 2005; 64(10): 1410 - 1413. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S Irvine and H C Capell Great expectations of modern RA treatment Ann Rheum Dis, September 1, 2005; 64(9): 1249 - 1251. [Full Text] [PDF]
|
|
|
|
|
|
E N van Roon, T L T A Jansen, M A F J van de Laar, M Janssen, J P Yska, R Keuper, P M Houtman, and J R B J Brouwers Therapeutic drug monitoring of A77 1726, the active metabolite of leflunomide: serum concentrations predict response to treatment in patients with rheumatoid arthritis Ann Rheum Dis, April 1, 2005; 64(4): 569 - 574. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 N. C. Andreasen, W. T. Carpenter Jr., J. M. Kane, R. A. Lasser, S. R. Marder, and D. R. Weinberger Remission in Schizophrenia: Proposed Criteria and Rationale for Consensus Am J Psychiatry, March 1, 2005; 162(3): 441 - 449. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P J Mease, C E Antoni, D D Gladman, and W J Taylor Psoriatic arthritis assessment tools in clinical trials Ann Rheum Dis, March 1, 2005; 64(suppl_2): ii49 - ii54. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S M M Verstappen, G A van Albada-Kuipers, J W J Bijlsma, A A M Blaauw, Y Schenk, H C M Haanen, J W G Jacobs, and on behalf of the Utrecht Rheumatoid Arthritis Coho A good response to early DMARD treatment of patients with rheumatoid arthritis in the first year predicts remission during follow up Ann Rheum Dis, January 1, 2005; 64(1): 38 - 43. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. H. Choy Two is better than one? Combination therapy in rheumatoid arthritis Rheumatology, October 1, 2004; 43(10): 1205 - 1207. [Full Text] [PDF]
|
|
|
|
|
|
J. Fransen, M. C. W. Creemers, and P. L. C. M. Van Riel Remission in rheumatoid arthritis: agreement of the disease activity score (DAS28) with the ARA preliminary remission criteria Rheumatology, October 1, 2004; 43(10): 1252 - 1255. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L Gossec, M Dougados, P Goupille, A Cantagrel, J Sibilia, O Meyer, J Sany, J-P Daures, and B Combe Prognostic factors for remission in early rheumatoid arthritis: a multiparameter prospective study Ann Rheum Dis, June 1, 2004; 63(6): 675 - 680. [Abstract] [Full Text]
|
|
|
|
|
|
J S Smolen and D Aletaha Patients with rheumatoid arthritis in clinical care Ann Rheum Dis, March 1, 2004; 63(3): 221 - 225. [Full Text] [PDF]
|
|
|
|
|
|
E Lindqvist, T Saxne, P Geborek, and K Eberhardt Ten year outcome in a cohort of patients with early rheumatoid arthritis: health status, disease process, and damage Ann Rheum Dis, December 1, 2002; 61(12): 1055 - 1059. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. F. Ferraccioli, R. Assaloni, E. Di Poi, E. Gremese, G. De Marchi, and M. Fabris Rescue of combination therapy failures using infliximab, while maintaining the combination or monotherapy with methotrexate: results of an open trial Rheumatology, October 1, 2002; 41(10): 1109 - 1112. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S Genevay, G Hayem, P Verpillat, and O Meyer An eight year prospective study of outcome prediction by antiperinuclear factor and antikeratin antibodies at onset of rheumatoid arthritis Ann Rheum Dis, August 1, 2002; 61(8): 734 - 736. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P Emery, F C Breedveld, M Dougados, J R Kalden, M H Schiff, and J S Smolen Early referral recommendation for newly diagnosed rheumatoid arthritis: evidence based development of a clinical guide Ann Rheum Dis, April 1, 2002; 61(4): 290 - 297. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. D. Smith, M. C. Kraan, J. Slavotinek, V. Au, H. Weedon, A. Parker, M. Coleman, P. J. Roberts-Thomson, and M. J. Ahern Treatment-induced remission in rheumatoid arthritis patients is characterized by a reduction in macrophage content of synovial biopsies Rheumatology, April 1, 2001; 40(4): 367 - 374. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A C Verhoeven, M Boers, and S van der Linden Responsiveness of the core set, response criteria, and utilities in early rheumatoid arthritis Ann Rheum Dis, December 1, 2000; 59(12): 966 - 974. [Abstract] [Full Text]
|
|
|
|
|
|
P. L C M van Riel and A. M van Gestel Clinical outcome measures in rheumatoid arthritis Ann Rheum Dis, November 1, 2000; 59(90001): i28 - 31. [Full Text] [PDF]
|
|
|
|
|
|
B. Harrison and D. Symmons Early inflammatory polyarthritis: results from the Norfolk Arthritis Register with a review of the literature. II. Outcome at three years Rheumatology, September 1, 2000; 39(9): 939 - 949. [Full Text] [PDF]
|
|
|
|
|
|
B. Svensson, C. Schaufelberger, A. Teleman, and J. Theander Remission and response to early treatment of RA assessed by the Disease Activity Score Rheumatology, September 1, 2000; 39(9): 1031 - 1036. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. T. H. Molenaar, W. F. Lems, B. A. C. Dijkmans, M. H. M. T. de Koning, R. J. van de Stadt, and A. E. Voskuyl Levels of markers of bone resorption are moderately increased in patients with inactive rheumatoid arthritis Rheumatology, July 1, 2000; 39(7): 742 - 744. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C H M van Jaarsveld, J W G Jacobs, M J van der Veen, A A M Blaauw, A A Kruize, D M Hofman, H L M Brus, G A van Albada-Kuipers, A H M Heurkens, E J ter Borg, et al. Aggressive treatment in early rheumatoid arthritis: a randomised controlled trial Ann Rheum Dis, June 1, 2000; 59(6): 468 - 477. [Abstract] [Full Text]
|
|